Tens of thousands of years ago... People wandered the earth, collecting and eating only what they found growing in nature. By about 8,000 BC, however, the first farmers decided to stay in one place and grow certain plants as crops — creating agriculture and civilization, in that order. Thousands of years ago People first learn to use bacteria to make new and different foods, and to employ yeast and fermentation processes to make wine, beer and leavened bread. 1700s Naturalists begin to identify many kinds of hybrid plants — the offspring of breeding between two varieties of plants. 1856 Gregor Mendel begins a meticulous study of specific characteristics he found in various plants which were passed to future plant generations. 1861 Louis Pasteur defines the role of micro-organisms and establishes the science of microbiology. 1900 European botanists use Mendel's Law to improve plant species. This is the beginning of classic selection. 1950 First regeneration of entire plants from an in vitro culture. 1953 James Watson and Francis Crick discover the double helix structure of deoxyribonucleic acid, commonly known as DNA. Proteins are made up of strings of amino acids. The number, order and kind of amino acids determine the property of that protein. DNA holds the information necessary to order the amino acids correctly. The DNA transmits this hereditary information from one generation to the next. But it wasn't until three decades later that even larger strides occurred in the field. Watson and Crick would later receive the Nobel Prize for their work. 1970s The Green Revolution introduces hybrid seeds into food-short Third World countries. 1973 Researchers develop the ability to isolate genes. Specific genes code for specific proteins. 1980s Scientists discover how to transfer pieces of genetic information from one organism to another, allowing the expression of desirable traits in the recipient organism. This is called genetic engineering, one process used in biotechnology. Using the technique of "gene splicing" or "recombinant DNA technology" (rDNA), scientists can add new genetic information to form a new protein which creates traits that protect plants from diseases and pests. 1982 The first commercial application of this technology is used to develop human insulin for diabetes treatment. 1983 The first transgenic plant: a tobacco plant resistant to an antibiotic. 1985 Genetically engineered plants resistant to insects, viruses, and bacteria are field tested for the first time. 1990 The first successful field trial of genetically engineered cotton plants (bt cotton) is conducted. DEKALB receives the first patent for transformed corn. 1994 The Flavr-Savr tomato, designed to resist rotting, is approved by the FDA for sale in the United States. 1995-1996 Monsanto's Roundup Ready soybeans, which are resistant to herbicides, and YieldGard Corn, which is protected from the corn borer, are approved for sale in the United States. Bollgard cotton first commercialized in the US. 1996 Posilac bovine somatotropin, designed to increase milk efficiency in dairy cattle, is approved for use in the United States. 1997 Roundup Ready cotton first commercialized in the US. 1998 DEKALB markets the first Roundup Ready corn. YieldGard® Corn is approved for import into European Union. 1999 President Clinton awards four Monsanto scientists National Medal Of Technology. 2000 Scientists achieve major breakthrough in rice; data to be shared with worldwide research community. On Nov. 27, President and CEO Hendrik Verfaillie announced the New Monsanto Pledge, the company's commitments to achieving sustainable agriculture.

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